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Caffeine is replaced by vitamin B3, which supports energy metabolism and contributes to the reduction of tiredness and fatigue

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While providing health literacy education to teach distinguishment of APAP and NSAIDs is important, some have thought it possibly more beneficial to mitigate the chance of inappropriate APAP over-ingestion by reducing the pack size of APAP preparations sold, which they believe may reduce the incidence and severity of APAP hepatotoxicity.7 What is clear is that APAP overdose and hepatotoxicity is a preventable public health concern that deserves awareness by both clinicians and the patient population alike